Which vaccine is contraindicated for individuals with a history of anaphylaxis to neomycin?

The correct answer is the Varicella vaccine, as it contains neomycin as one of its components. Individuals who have a history of anaphylaxis specifically to neomycin should avoid this vaccine due to the potential for a severe allergic reaction. Neomycin is an antibiotic that can cause allergic reactions in susceptible individuals, and since it is included in the formulation of the Varicella vaccine, administering it to someone with such a history poses a significant risk.

In contrast, the other vaccines listed do not contain neomycin in their formulations. The Influenza vaccine may utilize other preservatives or stabilizers but is not linked directly to neomycin hypersensitivity. The HPV vaccine and the Pneumococcal vaccine also do not have neomycin as a component, making them safe options for individuals with a neomycin allergy. Therefore, the identification of the Varicella vaccine as contraindicated is crucial in ensuring patient safety when considering immunization in individuals with a history of severe allergic reactions.